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Acute administration of the GLP-1 Receptor agonist lixisenatide diminishes postprandial insulin secretion in healthy subjects but not in type 2 diabetes, associated with slowing of gastric emptying

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The presence of an extra X chromosome (Klinefelter syndrome) or an extra Y chromosome, the presence of two X but no Y chromosome in a male, and microdeletions or translocations affecting the X or Y chromosome are examples of chromosomal problems that can disrupt sperm production and overall genital and gonad development, resulting in azoospermia (absence of sperm) and infertility