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Separately, Manchanda commented on Dr Reddy's receiving a complete response letter for its biosimilar Denosumab, calling it a setback in the companys effort to build a strong biosimilar portfolio and commercial presence in regulated markets

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This Lp(a) driven inflammation leads to endothelial dysfunction.[ref] Specifically, lipoprotein(a) and ApoA covalently bind with oxidized phospholipids at the site of distress or lesions in the endothelium

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