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Ginsenoside Rg3 significantly increased the expression of ULK1 and FUNDC1 in heart failure (HF) rats hearts, promoted the interaction of FUNDC1 and LC3 to initiate mitophagy, reduced the number of inflammatory cell infiltration, infarct size, and serum biomarker expression in HF rats hearts, and significantly decreased the mRNA expression of natural peptide predictor a (NPPA), NPPB, and the protein levels of Col and Col
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And for decades, neuroscience offered precious few tools to intervene once this cascade began
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