doi: 10.1016/j.semcdb.2015.12.015 17 PremontRTGainetdinovRR
Nowadays, FOXO4-DRI studies are focused on the following aspects: osteoarthritis (senescent chondrocyte clearance), metabolic dysfunction (insulin resistance and obesity-associated senescence), neurodegeneration (eliminating senescent brain cells), and fibrotic diseases (idiopathic pulmonary and liver fibrosis)
GLP-1: Different Paths to Weight Loss, One Goal Youve now met several promising Ozempic alternatives AOD-9604, 5-Amino-1MQ, CJC-1295/Ipamorelin, and MOTS-c each with a unique mechanism
PLoS ONE 14:e0224137 EFSA (2013) Scientific Opinion on the safety of advantame for the proposed uses as a food additive
Abbreviations ESKD: End-stage kidney disease GLP-1 RA: Glucagon-like peptide-1 receptor agonist HF: Heart failure ICER: Incremental cost-effectiveness ratio MI: Myocardial infarction NDSS: National Diabetes Services Scheme QALY: Quality-adjusted life year SGLT2i: Sodiumglucose co-transporter 2 inhibitor References McGuire DK, Shih WJ, Cosentino F et al (2021) Association of SGLT2 inhibitors with cardiovascular and kidney outcomes in patients with type 2 diabetes: a meta-analysis
Montoya, J
