Future research should focus on developing injectable intralesional systems, mucoadhesive topical formulations, and intraoperative implantable devices for precise, site-specific induction of regulated cell death
The Sp treated cells showed higher loads of reduced glutathione making them resistant to perturbation of antioxidant machinery or neurotoxin MPP +
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The incidence of sporadic ALS (SALS) in the 1990s in Europe and North America ranged from 1.5 to 2.7 per 100000 inhabitants per year, with an equal incidence in these regions (Wijesekera and Leigh 2009)
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