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A study from McMaster University found that even a short-term energy deficit can reduce postprandial myofibrillar protein synthesis by roughly 27% (Areta et al

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however, that may not always be the case

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The IGF-1 axis benefits from the same pause: it drifts back toward baseline instead of sitting chronically elevated, which is the safer position given GH/IGF-1s growth-promoting signaling

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Thyroid Tumors In animal studies, GLP-1 drugs have been linked to thyroid C-cell tumors

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