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Short-chain fatty acids and their association with signalling pathways in inflammation, glucose and lipid metabolism

EMJ 5 , 94103 (2020)

Reduced circulating IGF-1 and growth failure were also reported in T1DM patients, while IGF-1 concentrations in renal tissue were shown to be increased, suggesting increased local synthesis and/or IGF-1 sequestration from the circulation [203, 204]