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Detrimental impacts of pharmaceutical excipient PEG400 on gut microbiota and metabolome in healthy mice

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Their mechanism of action differs from traditional antibiotics, potentially reducing the likelihood of resistance development

GLP-1RAs disrupt this inflammatory cascade by diminishing adipose tissue macrophage infiltration, enhancing insulin sensitivity via reduced inflammatory signaling, and safeguarding pancreatic -cells from inflammatory harm (Pang et al

In other embodiments, PLGA copolymers with polyethylene glycol (PEG) are suitable polymeric matrices for the formulations disclosed herein