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Tolerability (e.g., gastrointestinal complaints and flushing) of the DMF drug was rated equal or better in most patients, showing that patients can switch form the traditional FAE mixture to the same dose of DMF with similar clinical relief but without any washout period

Patients on other dual therapy were switched to metformin HCl 1500 mg/day and rosiglitazone 4 mg/day in a dose titration/stabilization run-in period of up to 20 weeks in duration

Patients were randomly assigned to undergo either completion lymphadenectomy (n = 240) or observation (n = 233)

Magnesium, vitamin C, B vitamins, and zinc are key nutrients for healthy cortisol regulation

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