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Key Takeaways: Ozempic and Constipation Constipation affects 24% to 28% of people taking Ozempic Caused by slowed gut motility, reduced food intake, and decreased fiber consumption Most common during first weeks and after dose increases Usually improves within 2 to 4 weeks at each dose level Prevention focuses on aggressive hydration, adequate fiber, and regular movement Osmotic laxatives like polyethylene glycol are safe for regular use Stool softeners help but dont address root cause of slow motility Stimulant laxatives should be reserved for occasional use only Why Ozempic Causes Constipation Understanding the specific mechanisms behind Ozempic-related constipation helps you address it more effectively than generic constipation remedies