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Fed-batch fermentation was conducted in a 2.5 L bioreactor (Kobiotech Co., Republic of Korea) containing 1 L of either YP20D medium or a molasses/CSL-based medium

Cysteine helps to neutralize chemicals known as aldehydes, which are produced by air pollutants, drugs, and also by the liver as a byproduct of alcohol metabolism

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In clinical applications, numerous natural compounds, acting as endogenous activators of NRF2, demonstrate significant potential in alleviating intestinal disorders by promoting nuclear translocation and the expression of downstream antioxidant and anti-ferroptotic genes ( Uncontrolled lipid peroxidation is a hallmark of ferroptosis, with Acyl-CoA synthetase long-chain family member 4 (ACSL4) playing a central regulatory role in this process