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SIRT1 is part of a family of proteins called sirtuins, known as longevity genes. It uses NAD+ as a fuel source to repair DNA, reduce inflammation, and improve stress resistance

Bioorganic & medicinal chemistry, 26 (10), 2700-2707

demonstrated the efficacy of andrographolide, a diterpene lactone, in protecting the blood-brain barrier by inhibiting the CypA-NF-B-MMP-9 pathway, highlighting its dual anti-inflammatory and neuroprotective effects (Zhou X et al., 2024)

J Agric Food Res

This activation promotes synaptogenesis, neurogenesis, and neuronal survival by mimicking or potentiating brain-derived neurotrophic factor (BDNF)-like activity, enhancing synaptic connectivity and cognitive plasticity

Choosing between HGH vs