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In phase 2 trials, people lost anywhere from 7% to 24% of their body weight in 48 weeks, depending on the dose

Experimental investigations were conducted to assess the impact of ARA-290 on the survival mechanisms and functionality within ECFC (Endothelial Colony-Forming Cell) cultures

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Compared with injectable formulations, the spray can precisely target the areas requiring protection, avoiding the problem of excessive systemic pigmentation

Neither study directly compared compounds head-to-head in identical populations, making direct inference difficult