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Rats with acute pancreatitis had a 21% reduction in cardiac output, a 37% decrease in contractility, a 23% decline in diastolic tension, and a twofold increase in the cardiac tissue edema index [80]

Zhao M, Wang Y, Li L, Liu S, Wang C, Yuan Y, et al

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Burdo J, Dargusch R, Schubert D

A total of 56% and 44% of adults randomized to acmopatide does of 4.1 mg and 6.6 mg, respectively, achieved the ADA-recommended A1C target of less than 7%, compared with 33% in the placebo group