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Regular kidney function monitoring (eGFR, uric acid) every 612 months during GLP-1 use supports early detection of adverse trends

Tseng, M

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GLP1 is an intestinal peptide, which was known to have a role in glucose homeostasis via actions that include the potentiation of glucose-induced insulin secretion and the suppression of glucagon secretion [30]

Most research, however, shows a clear dose-response relation

The study was sponsored by Eli Lilly and Company, the manufacturer of orforglipron and the injectable GLP-1, tirzepatide Side-effects were similar to other GLP-1s, including mild to moderate nausea, diarrhoea, constipation and bloating Its important to highlight that the study was quite small (just over 100 people in each arm of the study received active treatment), so more research is needed over a longer time period, says Dr Cork