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Its easier for patients to be consistent, and we know we need consistency to see results, she explains

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Alcohol should be minimized or eliminated during this protocol

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Moreover, these analyses have already been done in conventional meta-analyses, showing for SGLT-2 inhibitors the lack of significant difference in the reduced risk of the composite outcome (CV death + HHF) in patients with or without type 2 diabetes or in subjects of 65 years of age or younger vs those older than 65 years of age [13]