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OPZ concentrations were 0 (), 25 (), 50 (), 75 (), and 100 () M

The goal is to understand why inflammatory signaling is elevated and whether modifiable drivers are present: visceral fat, periodontal disease, poor sleep, alcohol, insulin resistance, autoimmune activity, environmental exposure, chronic infection, or unresolved cardiometabolic risk

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Deletion analysis has revealed that the essential portion of the promoter is only about 150 base pairs long