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In mouse ischemia-reperfusion models, this produces approximately 50% reduction in infarct size

It is found in virtually every cell of the body and plays a critical role in protein synthesis, synthesis and repair of DNA, enzyme function, transport, and cell maturation

Schwartz EA, Reaven PD

Review of epidemiological and preclinical studies

It also has been described that -glutamylcysteine, the intermediate of GSH biosynthesis, is able to act as a Gpx1 cofactor in mitochondrial H 2 O 2 detoxification, mimicking the physiological properties of GSH (Quintana-Cabrera et al., 2012)

Lower doses are still highly effective