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Obesity disrupts bone metabolism and leads to increased bone resorption, but GLP-1RAs can inhibit this damage and improve bone health by increasing the OPG/RANKL ratio, reducing osteoclast activity, and promoting bone formation

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Emerging studies suggest possible benefits in glaucoma, ocular surface disease, and some retinal vascular outcomes, while evidence for age-related macular degeneration and cataract remains limited or conflicting

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