retatrutide works (“reta”) is an experimental weight-loss drug currently in Phase 3 clinical trials. It's a once-weekly injection similar to Ozempic and Mounjaro—but more powerful. The reason comes down to how it Retatrutide Guide 2023: Weight Loss,

[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Jastreboff AM, Kaplan LM, Fras JP, Wu Q, Du Y, Gurbuz S

Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes

Pinto, an obesity and family medicine doctor at Johns Hopkins Medicine in Baltimore, who wasnt involved in the research

Possible side effects Nausea Diarrhea Decreased appetite Vomiting Constipation Dyspepsia (indigestion) Abdominal pain If side effects are severe or persistent, contact your healthcare provider

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Tirzepatide side effects tend to be at their worst during a dosage increase and tend to become less frequent over time as your body adjusts to the medication