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Cagrilintide versus retatrutide Retatrutide adds glucagon receptor activation to GLP-1 and GIP agonism, creating a triple-agonist profile
doi: 10.1073/pnas.94.5.1967
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Albiglutide is generated from a genetic fusion of two modified recombinant GLP-1 (36) molecules linked in tandem to recombinant human albumin (90), while dulaglutide is created by conjugating two GLP-1 (37) analogues to the Fc fragment of a modified monoclonal antibody (IgG4) via peptide ((Gly 4 Ser) 3 Ala) linker (91)
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