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doi: 10.3389/fphys.2021.754638 Received 06 August 2021 Accepted 05 October 2021 Published 05 November 2021 Volume 12 - 2021 Edited by Helene Guizouarn, Centre National de la Recherche Scientifique (CNRS), France Reviewed by John Stanley Gibson, University of Cambridge, United Kingdom

Ghrelin, the hormone that makes you feel hungry, also showed a downward trend in one study, and resistin dropped in another

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If six months of consistent, properly-dosed application produces no noticeable change, alternative approaches may be needed

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