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In addition, a deficiency of vitamin B12 can cause facial signs such as hyperpigmentation (dark spots), vitiligo (white patches where skin loses color), or angular stomatitis (inflammation at the corners of the mouth)

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Rather than having specific and direct benefits for health, natural settings for performing PA, sports, and exercise promote health-enhancing behavior (155160)

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The table below summarizes the state of evidence by area, distinguishing between the animal data that exists and the human data that does not

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FcRn antagonism by use of IVIg and an IgG1 mAb specific for rat FcRn has been shown to prevent this disease and protect the fetus in disease modeling studies in mice [348, 349], suggesting a potential therapeutic avenue for FcRn antagonism in the clinic for this and similar diseases

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