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The levels of serum ALT, AST, ALP, and LDH were also markedly elevated

The activity of mTORC1 is primarily mediated by phosphatidylinositol-3-OH kinase/RAC- serine/threonine-protein kinase/tuberous sclerosis complex (PI3K/AKT/TSC) and liver kinase B1/the mitogen-activated protein kinase (LKB1/AMPK) axis

doi: 10.1111/sji.12998 14

TB-500, with its systemic action, may be particularly useful for cervical herniations since it does not require injection near the sensitive cervical structures