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Nurs Clin North Am
Animal data showing endogenous IGF-1 suppression during LR3 use (Bastian et al., 1995
These conditions include metabolic syndrome [11, 12], diabetes [4], high blood pressure, atherosclerosis [13], ischemia-reperfusion injury [13], cancer [14, 15], and various neurodegenerative disorders [16]
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In SURPASS-2, which compared tirzepatide to semaglutide 1 mg in 1,879 patients with type 2 diabetes, tirzepatide 5 mg, 10 mg, and 15 mg reduced systolic blood pressure from baseline by 5.6, 7.4, and 8.0 mmHg respectively at 40 weeks, compared to 5.3 mmHg with semaglutide
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