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References Solano F
Physiology 235 (10), 66476659
Regardless the differences in their chemical structure and metabolic pathways, gliptins as a group constitute a widely accepted therapy for the management of T2DM, usually as a second-line medication [27, 42, 153156]
Chronic inflammatory response Long-term accumulation of platinum in multiple tissues can induce the generation of a large amount of ROS, promote the sustained release of pro-inflammatory cytokines such as TNF-, IL-6, and IL-1, and form a systemic chronic low-grade inflammatory microenvironment, which is the core driving mechanism of CRF (Bower and Lamkin 2013)
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