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Cancer Sci (2013) 104:43744

Half of the worlds population could be living in areas facing water scarcity by as early as 2025

We also demonstrated that ectopic expression of wild-type mTOR, constitutively activate S6K1, or downregulated 4E-BP1 partially prevented rotenone-induced neuronal apoptosis, suggesting that rotenone-induced neuronal loss in PD may be prevented by activating mTOR signalling 15

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However, this acute oxidative stress serves as a hormetic stimulus that triggers adaptive responses, including upregulation of endogenous antioxidant systems including glutathione synthesis