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Epalrestat and DOX were co-delivered at tumor targeted site using redox-sensitive polymer micelles composed of tocopherol polyethylene glycol succinate conjugated with vitamin B6 which acts as cancer targeted moiety [281]

5 Despite the lack of long-term safety data and the presence of unidentified impurities (4.1%-5.9%) in commercially available products, the majority of respondents (93%) indicated that they planned to continue using melanotan, stating that it increased their self-perceived attractiveness and overall quality of life

That most anti-cancer drugs are poor substrates for GSTP indicates that the role of elevated GSTP in many tumor cell lines is not to detoxify the compounds, but must have another purpose

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