Recommendation: No b12 supplementation needed at start
However, human clinical evidence is still limited, and larger, well-controlled trials are needed to clarify safety, efficacy, and appropriate use
10.1002/elsc.202000077 16 HkkinenS
Recalls & Warnings May 01, 2023 TruVision Recalls Products Due to Presence of Potentially Dangerous Ingredients On April 27, 2023, TruVision Health issued a recall of various dietary supplement products because they contain hordenine and/or octodrine/DMHA, compounds that the FDA considers to be possibly unsafe and which are not permitted to be sold as dietary supplements
In a 23-week randomized clinical trial in humans, individuals taking AOD-9604 at 1 mg daily had an average of 2.8 kg weight reduction compared to a 0.8 kg weight reduction in those taking a placebo
But in the Retatrutide Phase 2 Obesity trial, Low Wang said that 100% of study volunteers who received 8 milligrams or more of the medication rather than the placebo lost at least 5% of their body weight