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These costs are largely driven by the need for complex production and formulation strategies to address challenges such as poor protein stability and solubility, both in vitro and in vivo, as well as rapid degradation and short half-life, which often necessitate frequent dosing or molecular modifications
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PMID: 26311425
10.1111/and.12196 65 SaleemA.SaleemM.AkhtarM
A severe, destructive form of psoriatic arthritis known as arthritis mutilans afflicts a subset of patients
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