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Supplementary Material Acknowledgments We thank Carla Bartels (Medical Microbiology Department, Radboudumc) for culturing Bb spirochetes

Pick one and optimize that dose before stacking them

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In mouse models treated with intraperitoneal injections of potassium oxonate and oral administration of xanthine, Morin, a principal component of Gouji [Maclura cochinchinensis (Lour.) Corner heartwood] extract, can inhibit XOD activity in a non-competitive manner, lowering serum UA levels (29)

Common side effects: AOD 9604 has essentially none (indistinguishable from placebo)

Researchers working with KLOW should maintain documentation of the research purpose and institutional context of use, consistent with standard laboratory materials management practices