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,,FaraonioR,VergaraP,Di MarzoD,PierantoniMG,NapolitanoMRussoTet al.p53 suppresses the Nrf2-dependent transcription of antioxidant response genes.2006;281(52):3977639784

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There's research suggesting an association between estrogen and cognitive function, and the timing hypothesis is relevant here too: early initiation of HRT is studied differently than late initiation for cognitive outcomes

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