Semaglutide has been on the market longer, which means more real-world safety data, broader insurance coverage, and greater familiarity among prescribers
Ozempic compared to Trulicity led to: lower blood sugars based on HbA1c by about 0.3%(-1.4% vs -1.1%)
This is often closely intertwined with mast cell activation syndrome (MCAS), where accumulated toxins and chronic oxidative stress cause mast cells to become hyper-reactive, constantly degranulating and releasing histamine and other inflammatory mediators into the bloodstream
In clinical trials, the most common side effect was headaches, occurring in 6% of users, followed by drooping eyelids in 2% of users, and facial asymmetry in 1% of users
C., Loscalzo J
In most cases, the body gradually adapts to treatment