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In HT, the vitamin D-induced prevention of dendritic cells- dependent T-cell activation and inflammatory cytokines production and the restoration of the anti-inflammatory state through a restoration of the Th17/Treg ratio has been claimed as one of the beneficial mechanisms (68, 69)
Some researchers have found that miR-382-5p expression is down-regulated and SLC7A11 expression is up-regulated in ovarian cancer tissues, and lidocaine targets the miR-382-5p/SLC7A11 axis (which up-regulates miR-382-5p expression and down-regulates SLC7A11 expression) to promote ferroptosis in ovarian cancer cells and exert anti-tumor activity (97)
However, if the recommended dose is significantly exceeded, it can lead to unpleasant side effects (NIH, 2023)
Effect of epidermal growth factor (EGF) and polyamines on the healing of gastric mucosal lesions induced by ischemia-reperfusion
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