Another study developed airliquid interface (ALI) endometrial assembloids combining stromal and epithelial cells within a matrix, mimicking the human endometrial anatomy with stromal, glandular and luminal epithelia, and showing menstrual cycle-related hormone responses, gene expression and dynamic ciliogenesis [86]
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It promotes fibroblast proliferation, stimulates collagen and elastin synthesis, activates antioxidant defense enzymes, and has documented anti-inflammatory effects
Quinn MJ, Crotty KA, Thompson JF, et al
Tutwiler V, Mukhitov AR, Peshkova AD, Le Minh G, Khismatullin RR, Vicksman J, et al