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Preclinical pharmacoscintigraphic imaging and studies in canine models have demonstrated that semaglutide is primarily absorbed in the stomach, with higher drug concentrations detected in the splenic vein relative to the portal vein, indicating site-specific uptake [51]

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But its backed by gene expression studies showing that GHK-Cu modulates over 4,000 human genes, with a significant portion involved in tissue remodeling, antioxidant defense, and stem cell function [3]

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