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The key limitation is evidentiary rather than safety-related

Most patients with IC/BPS report a history of urinary tract infection and have received several courses of antibiotics based on their symptoms, not on positive urine cultures

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The animals were group-housed until one week before treatment initiation, after which they were given daily subcutaneous injections of vehicle or Cagrilintide at doses of 0.3, 3, or 30 nmol/kg for 21 days

Some are research-grade peptides used in clinical settings, while others are low-dose, supplement-style capsules with little proven efficacy

PMID 20143256 Pfizer/Hospira