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In the non-T2D cohort, participants were matched and compared after six months of treatment with either tirzepatide (cohort 1a, n = 6923) or semaglutide (cohort 2a, 6923), with a follow-up of 12 months to assess the incidence of T2D and changes in glycated hemoglobin (HbA1c), body weight, hypoglycemia, and acute pancreatitis

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Appropriate diabetes treatment which may include semaglutide can help prevent long-term health problems like heart disease, kidney disease, and vision problems

CKD is often not detected until it has reached an advanced stage (NIH 2008