In contrast to the lead candidate described above, GQB47810 and neuromedin C, exhibited lower GLP-1R agonistic activity (Figure cAMP)
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Shaded diamonds represent intracellular drug and drug metabolites
JAMA Netw Open 7(8):e2423385 Zhou J, Huang W, Xie Y, Shen H, Liu M, Wu X (2025) Risk of ophthalmic adverse drug reactions in patients prescribed glucagon-like peptide 1 receptor agonists: a pharmacovigilance study based on the FDA adverse event reporting system database
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This was highly significant compared to the placebo group