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To our surprise, we also observed a convergence and accumulation of mGs-positive vesicles to the Golgi apparatus suggesting that GLP-1R may engage in endosome-to-Golgi retrograde transport while continuing to sample a conformation that can elicit additional waves of signaling (Fig

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They are grouped as a research convenience, allowing researchers to work with a consistent, standardised composition and reducing variability associated with separate sample preparation in the laboratory

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