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Hobbs CJ, Plymate SR, Rosen CJ, Adler RA

Cellular senescence is characterized by a stable arrest in the cell cycle and encompasses a range of cellular changes that culminate in the development of a complex, pro-inflammatory secretory profile known as the senescence-associated secretory phenotype (SASP), which plays a critical role in fibrosis and tumors by affecting numerous processes, including invasion and therapy resistance 10

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During viral infections the activation of inflammatory T-cell phenotype can be associated with virus eradication

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Current Research Areas Current literature and supplier documentation are reviewed in the context of compound identity, lot consistency, assay suitability, and controlled research workflow design