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3.5 GHK-Cu regulated the SIRT1/STAT3 pathway SIRT1, which is closely associated with cellular metabolism and stress responses, also interacts with the STAT3 pathway (Wu Q

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By stimulating angiogenesis within bone tissue and enhancing osteoblast activity via VEGFR2-NO signaling, BPC-157 markedly improves bone matrix deposition and fracture consolidation, highlighting its clinical promise for orthopedic conditions [20, 26]