Rapid weight lossa primary effect of tirzepatide therapycan shift hair follicles prematurely from the active growth phase (anagen) into the resting phase (telogen)
Immunology (2009) 126(1):6373
The peptide repairs intestinal mucosal damage, restores tight junction integrity reducing intestinal permeability often called leaky gut, normalizes gastric emptying and intestinal motility, protects against NSAID-induced ulcers, and promotes healing of inflammatory bowel disease lesions
For example, most clinical trials reporting weight loss outcomes involved participants taking 2.4 mg of semaglutide, which is the maximum dose for Wegovy
doi:10.1038/s41598-023-29276-7
In contrast, it would be easy to find five heads in a row when searching through 100 consecutive coin flips, and that finding would not be considered statistically significant