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sustained results require coordination across disciplines

Proc Natl Acad Sci U S A 89: 8641-8645, 1992

Central and peripheral nervous system disturbances, including altered brain processing, downregulated pain inhibition, and mechanosensitive ion channels (e.g., Piezo2, TRPV1), underpin chronic pain in IBS-C, while their role in FC remains unclear

Functional brain imaging studies have reported a decrease in synaptic connectivity and neuronal circuitry in the PFC and hippocampus in depressed patients (Perlman et al., 2012

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I certainly never imagined that, decades later, gut physiology would become central to my own work through GLP-1 biology