Updated 20242025
The PlexusDx Precision Peptide Genetic Test identifies variants in key genesincluding GLP1R (rs6923761), MC4R (rs17782313), FTO (rs9939609), and GIPR (rs1800437)that influence GLP-1 sensitivity and metabolic predisposition
No Observed Effects On: Blood glucose or insulin sensitivity (no diabetogenic effects) IGF-1 levels (remained within normal ranges) Blood pressure or cardiovascular parameters Thyroid function Liver or kidney function markers Important: The absence of growth hormone-related side effects distinguishes AOD-9604 from full-length GH, which can cause fluid retention, joint pain, carpal tunnel syndrome, and insulin resistance
Furthermore, treatment with the ferroptosis inducer erastin (10 M) led to an additional increase in MDA levels in SYNCRIP KO cells compared with controls, whereas treatment with the ferroptosis inhibitor ferrostatin-1 (Fer-1
Slow dose escalation, dietary adjustments, and regular patient education are key strategies
The most common side effects are gastrointestinal, including nausea, constipation, or diarrhea, especially when beginning treatment
