doi: 10.3389/fimmu.2022.1098725 237 NiuYChenXXiaoLLiWFengLAierkenA
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Non-responsiveness typically indicates one of three issues: the peptide has degraded (common if stored improperly above 4C), baseline synaptic density is already optimal (meaning Dihexa has little substrate to act on), or co-factors required for synaptogenesis (adequate sleep, dietary choline for acetylcholine synthesis, omega-3 fatty acids for membrane remodeling) are insufficient
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