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doi:10.21053/ceo.2022.00815

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According to a 2012 review, 29 is the minimum required for complete biological activity.9 The structural difference here means that tesamorelin is a stabilized analog that more closely mimics the hormone on which its based.28 Pharmaceutical status While sermorelin has been discontinued as an FDA-approved drug for growth hormone deficiency, tesamorelin is currently approved as a treatment for HIV-associated lipodystrophy (an accumulation of excess abdominal fat resulting from HIV)

These peptides together increase metabolic rate and encourage the body to use fat for fuel, as evidenced by users seeing decreased abdominal fat over a few months

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