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Body measurements show waist decreasing while arm and leg circumference holds steady or even increases slightly as body fat percentage drops

Hold at each step for at least two weeks before increasing

On the other hand, the effect of weight loss in late stage might be not as satisfied as that in the early stage

p 40% to meet its primary endpoint, addressing a prominent and longstanding therapeutic challenge, since HFpEF constitutes about half of patients with chronic HF and historically has lacked therapies that modify cardiovascular outcomes

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The thyroid scan was within normal limits