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This might be beneficial or problematic depending on baseline blood pressure and the degree of medication effect

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N Phytol 225:488498 [DOI] [PMC free article] [PubMed] [Google Scholar] Martelli G, Giacomini D (2018) Antibacterial and antioxidant activities for natural and synthetic dual-active compounds

[8] Very high doses may occasionally cause hypokalaemia (low potassium), particularly in patients with severe megaloblastic anaemia when treatment is initiated, necessitating monitoring in hospital settings

Furthermore, the appendix contains mucosa and submucosa rich with macrophages, follicular dendritic cells, and lymphocytes, which aid in detecting and tolerizing the body to host and foreign antigens (Kooij et al., 2016)