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Researchers conducted 1:1 propensity-score matching based on age at index date/demographics, initial BMI, prior follow-up, and mortality predictors

Written informed consent by the patients was waived due to a retrospective nature of our study

Pentoxifylline improves nonalcoholic steatohepatitis: a randomized placebo-controlled trial

While semaglutide reduces appetite in most users, weight gain occurs when calorie intake exceeds expenditure despite medication, often from tolerance development, compensatory overeating during symptom plateaus, or increased insulin sensitivity driving food calories into fat storage

As we age, telomeres shorten, leaving the information crucial for healthy cell function vulnerable

Please note that while these drugs offer new therapy options for obese patients and for patients with type 2 diabetes, they are not a permanent solution and are no replacement for an appropriate diet coupled with the right amount of exercise